Commonly invasive serotypes ofStreptococcus pneumoniaetrigger a reduced innate immune response compared with serotypes rarely responsible for invasive infection
نویسندگان
چکیده
منابع مشابه
Emerging resistant serotypes of invasive Streptococcus pneumoniae
BACKGROUND Streptococcus pneumoniae is the leading cause of meningitis and sepsis. The aim of the study was to analyze the distribution, vaccine serotype coverage, and antibiotic resistance of S. pneumoniae serotypes isolated from patients with invasive diseases, after the introduction of pneumococcal 7-valent conjugated vaccine (PCV-7). METHODS A total of 134 isolates were collected from blo...
متن کاملSimultaneous identification of 29 prevalent invasive pneumococcal serotypes or pairs of serotypes by hybridization-ligation PCR.
A hybridization-ligation PCR assay was developed for the simultaneous detection and identification of 21 pneumococcal serotypes and 8 pairs of serotypes in the same serogroup: 1, 2, 3, 4, 5, 6A, 6B, 6C-6D, 7F-7A, 8, 9A-9V, 9N-9L, 11A, 14, 15B-15C, 16F, 17F, 18B-18C, 19A, 19F, 20, 21, 22A-22F, 23A, 23B, 23F, 28A-28F, 35B and 38. This novel assay was validated with 185 serotyped pneumococcal inva...
متن کاملInvasive pneumococcal infection in a healthy infant caused by two different serotypes.
We present a case of invasive pneumococcal infection in a healthy 10-month-old infant from whom Streptococcus pneumoniae serotype 23F was isolated from the blood and serotype 23B was isolated from the cerebrospinal fluid. Both serotypes were penicillin nonsusceptible. Pulsed-field gel electrophoresis analysis demonstrated that the two serotypes had distinct DNA patterns, indicating that infecti...
متن کاملPneumococcal serotypes associated with invasive disease in under five children in India & implications for vaccine policy
BACKGROUND & OBJECTIVES Streptococcus pneumoniae is a major cause of morbidity and mortality especially in children less than five years, particularly in India. We present data on S.pneumoniae infections in children less than five years age group, with response to its serotype distribution, antibiotic resistance profile and available vaccines expected coverage. METHODS Children aged less than...
متن کامل968Changes in Serotypes of Group B Streptococcus in Infants with Invasive Bacterial Infection in Korea; from 1994 to 2013
Invasive Bacterial Infection in Korea; from 1994 to 2013 In Ae Yoon, MD; Young June Choe, MD, MPH; Hyunmi Kang, MD; Hyunjoo Jung, MD; Jae Hong Choi, MD; Eun Young Cho, MD; Dae Sun Jo, MD, PhD; Hyunju Lee, MD, PhD; Eun Hwa Choi, MD, PhD; Hoan Jong Lee, MD, PhD, FIDSA; Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Pediatrics, Seoul Nati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2008
ISSN: 0928-8244,1574-695X
DOI: 10.1111/j.1574-695x.2008.00382.x